Best political organizations to make large donations to?

So I grew up in a conservative state in the midwest and have since become quite successful.

I have grown tired of conservatives having no policy platform, and their culture war bullshit is now negatively impacting medium and large businesses as they rock the boat too much and force us to take a public stand in favor of basic human rights which just fuels more culture war.

So...since this rocky and completely needlessly turbulent political period is going to cost money anyway, I've decided to throw some cash at the democrats. I'm not looking to give huge amounts to nationally recognized candidates because they have enough money already, and I want to make a difference on the state level.

Problem is, I see about 50 different organizations with overlapping missions and no history of what they have accomplished.

Does anyone know the best place to donate for basic things like GA state house, senate, SOS, etc? I'm already aware of Act Blue, but again, there's like 50 organizations and no explanation (disorganization is one of the reasons I didn't become involved with democrats earlier in life...)

I've talked to some consultants and one idea is to direct money against conservative incumbents in non-elections years through advertising and protest, just to make their lives harder and make the job less appealing to them to see if that doesn't reign in their bad behavior. But again, I see NO organized attempt to do this. I'm not looking to start my own political organization here, but the democrat infrastructure here is under-baked.

What would really make a difference? Thanks.