Tohoku road trip

Hi all, I am going back to Japan next year and I wanted to spice things up with a road trip in north Japan (mainly Tohoku). I will be with a friend, so Tokyo is a must at the start.

Here is the itinirary I was thinking, keep in mind it's noly the coties, but the region around them. I am used to long road trips in Europe, distance is not a problem: Tokyo - 3 days

Kamakura - 2 days

Sendai - 2 days

Hiraizumi - 1 day

Shimokita peninsula - 1 day

Hirosaki - 2 days

Aomori - 1 day

Kakunodate - 1 day

Ginzan - 1 day

Yamagata - 2 days

Aizo Wakamatsu - 2 days

Nikko - 2 days

So my question is what would you do for car rentals? I'm not sure if it would best to start our road trip from sendai or just from Tokyo. Any tips?