Anyone having any regrets about buying their home?

Just curious. My spouse (32F) and I (32M) have been discussing whether or not we should start looking to buy our first home. We have 2 young kids (under 3) and live in a VHCOL area.

We see a lot of our friends and family starting to buy homes but in mostly MCOL areas, she thinks we should move to one of the areas to get a home but I’d think we’d regret it since there are better career opportunities for me where we currently are. We currently rent and enjoy the area we’re in but ngl do feel like we are “behind” by not owning a home. Curious if there’s anybody else who bought and has any regrets or anything you wish you considered more.