High IL-10 & Cortisol

I'm waiting for my follow-up appointment with an autonomic neurologist, but my guess is that I will continue to be a confusing treatment resistant mess.

My cytokines are normal, except I've had two blood tests with high IL-10, which when chronic has been liked to chronic fatigue. I also had high morning cortisol for the first time, as well as a speckled ANA titer (used to be negative). I don't have symptoms of any auto-immune disease, and blood tests for a few have them have been negative.

So both IL-10 and cortisol calm down the immune system. I am also hypermobile, have POTS and have histamine food reactions in my (and high levels in my blood). And reactive hyperglycemia and hypersensitive fasting hypoglycemia even though my blood sugar levels are within range.

I have had issues for years, but it's just been within the last 2 years that I have really gotten worse. My biggest complaint is depression - which gets worse with too much activity. (stupid doctors need to understand that.)

Any ideas? Please no suggestions on diet. I probably need more blood tests to confirm anything, but my guess is that I won't have anything that fits a certain profile. He is also going to go over my neck MRI because my autonomic reflexes are exaggerated and the hypermobility may have compromised my spine (however the MRI results weren't conclusive).

I'm sick of my body being at war. I may eat something that makes my gut feel healthy, but then gives me a histamine reaction. And I have limited control with eating in ways to lower my MAST cell reactions, because then my hypoglycemia makes me more weak. Not only do I have exercise intolerance, but I have low blood sugar intolerance (if I don't eat enough, I am also weaker the next day). Try losing weight with this predicament! Feeling hopeless.

I do find Cromolyn Sodium can help my histamine reactions, no POTS medications have worked. Super sensitive to meds. LDN helps my depression and food sensitivities but makes me weaker.