Can 5 reapers defeat the halo universe in the year 2525?

Setting is the halo universe in the year 2525 when humanity and the covenant have just made first contact.

5 reapers from the mass effect universe have awoken unbeknownst to humanity or the covenant. Likewise the reapers have no knowledge of the halo galaxy. However, the reapers programming still forces them to reenact the harvesting cycle.

Halo universe physics apply but the reapers will be allowed to use whatever element zero they have within them to its full effect. No other element zero deposits exists in the setting.

Can the reapers do it?