Base 341 Hours

I just created science 3 (logistics science pack) for the first time. My base makes around 220 items. My science production is designed to run at 5 science 1 a second, 2.5 science 2, and whatever the appropriate ratio is for science 3. But some things are still holding it back and need to be upgraded. I have 1,200 "wind fish turbines" and 11 geothermal vents. My base contains lots of small production and some mega blocks. The science 1 mega block has 28 trains feeding it. I have 286 trains total and 507 stations. This game is a monster.