HA File Server in a virtualized environment: what do you use?

I'm on course to migrate our current RDP + UPD to FSLogix, as well as set up a new environment, also with FSLogix, both almost entirely on-prem, no 365. The profile disks are currently residing on a SOFS created with two VMs in S2D, and I'm wondering what you guys use or suggest.

The current solution is reliable enough, but performance of S2D on VMs, even with SR-IOV and RDMA, isn't very good. The advantage is that, even though only on the storage owner, VM-level snapshots and backups still work.

A (much) higher performance alternative is the use of shared virtual drives (vhd set in the hyper-v world), but that forces you out of VM-level backups, leaving you up to OS-level, agent-based backups. Not ideal in case of certain disaster scenarios.

For pure file servers, I still prefer the convenience of multiple single vm file shares, organized in DFS namespaces, to retain shadow copy and quick backup/restore functionality. Losing a single share for short amounts of time in case of emergency is not that big of a deal - but that is not the case for user profiles, in a 24/7 company.

So I wonder... how do you like your file storage in fully virtualized on-prem scenarios? Is there a decently performant yet convenient solution?

**Edit: from reading further into the documentation, for fslogix specifically the built in redundancy should suffice. Still curious about what other people use for highly available application file servers though.**