Time Zones for Remote

I’m (forever) casually looking and just saw a full remote job pop up today that would check all or most of my boxes. I live in Hawaii, my whole family and life is here, I’ve been here for 20+ years and I’m not moving. I say this just to clarify that I’m not a recent transplant who came to Hawaii to take advantage of telework and wants to stay, but could easily leave. No judgement there, just that I’m pretty much only open to remote jobs because I’m not qualified for or interested in the Federal jobs located on Oahu or in relocating.

So on to the question - are remote jobs expected to be working during business hours of the home office?

This would be a killer for me because we are 5 or 6 hours behind EST where the agency I’m interested in is based.

Thank you!!